After upgrading Medion Akoya MD 98930 (E6634) to Windows 10, the laptop would not wake up from sleep. Multiple restarts were needed and it was massive PITA.
I have tried all the solutions of turning off Hibernate, Hibernate Sleep and other tricks that can be found around the internet, but with no success.
The solution was upgrading the BIOS to the latest revision.
Download the file, save all your open work and run the file as administrator.